You won’t need to disengage the brakes if they are disc brakes. If the bike has hydraulic disc brakes, do not squeeze the lever while the wheel is out.
In a pinch, you can patch a punctured bike tube without removing the entire wheel — although it makes the actual patching job more difficult — but you have to remove the wheel to replace the tube. [5] X Research source
Schrader valves are the same type found on car tires. Presta valves are thinner and longer than Schraders, and have a locknut at the tip. Dunlop valves are thinner than Schraders and thicker than Prestas, and threaded only near the top. If your wheel has a lock ring that screws onto the valve stem to hold it to the bike rim, remove it after deflating the tube — but don’t lose it!
To reduce the risk of damage to your wheel frame, buy a set of inexpensive bike tire levers for the job — you can get them at any bike shop or online. A pair of spoon handles or flathead screwdrivers will work as levers, but you have to insert and pry with them carefully so you don’t scratch up or bend your wheel frame.
If you’re replacing the old tube due to a puncture, check the inside of the outer tire for sharp objects and holes larger than 0. 25 in (0. 64 cm), which will mean you need to replace the whole tire. Use a flashlight for a visual inspection, and/or run a thick cloth around the entire inside. Carefully remove anything you find. Do this before you move on to installing the new tube, or you may just end up with another flat tire!
You may also use a set of plastic tire levers for this part if you are unable to do it by hand. However, be careful not to puncture the tube with the levers.
An improperly inflated tire is more likely to puncture.
If your bike has a quick release mechanism for the wheels, just close the latch to secure your wheel. Now you’re ready to go for a ride!