Wrap the bristles in a plastic bag for 1 hour after applying the conditioner so it absorbs deeper. You do not have to rinse the conditioner out of the brush. [2] X Research source

Avoid using dish soap on natural-hair paintbrushes meant for oil paint since you could damage the bristles.

You can use laundry detergent if you don’t have any fabric softener. [5] X Expert Source Patrick CoyePainting Specialist Expert Interview. 19 August 2020. You don’t need to rinse your brush after using fabric softener since it actually helps prevent paint from sticking to the bristles the next time you use it. Fabric softener also works to soften new or dried out brushes.

In a pinch, you can also use nail polish remover since it normally contains acetone. If there’s still some stubborn pain in the bristles, try soaking your brush in acetone overnight again.

If the bristles feel dried out after using rubbing alcohol, rub some soapy water on them when you finish cleaning.

You can instead use coconut oil or linseed oil made for cleaning paintbrushes.

You can use mineral spirits or paint thinner to clean acrylic brushes or oil brushes. Paint thinner can irritate your skin, and it produces harmful fumes. Work in a well-ventilated area and wear a respirator and rubber gloves when you work with it so you stay safe. [11] X Research source Paint thinners can damage brushes and make the bristles fall out after repeated uses.

Just make sure that you don’t pull the comb too forcefully since it could loosen the bristles and make them fall out. [13] X Expert Source Patrick CoyePainting Specialist Expert Interview. 19 August 2020.