How long you need to stay on HRT may depend on your condition and your doctor. While you can technically use hormones indefinitely, many doctors will stop treatment after 2-5 years. While each case can vary, it is generally recommended that transgender individuals remain on HRT until they are 50 to reduce the risk of osteoporosis. [3] X Research source
If you used HRT to ease menopause, symptoms may return, including hot flashes, vaginal dryness, anxiety, mood swings, muscle aches, or a reduced sex drive. If you had a history of vasomotor issues (such as hot flashes or heart palpitations) before taking HRT, ask your doctor how you can manage your symptoms once you have stopped taking hormones. While HRT can prevent osteoporosis from developing, your risk may return if you stop taking HRT.
Gradually stopping HRT may reduce the risk and severity of side effects.
If you are going through menopause, exercise can reduce hot flashes. If you have recently stopped taking testosterone or estrogen, you may be at increased risk of weight gain. You can use exercise to maintain or lose weight. [11] X Trustworthy Source HelpGuide Nonprofit organization dedicated to providing free, evidence-based mental health and wellness resources. Go to source
In most cases, your doctor will scan your bones using a DEXA machine to determine your risk of getting a bone fracture. Staying active and taking supplements with calcium and vitamin D may be able to help protect your bones. [13] X Trustworthy Source National Health Service (UK) Public healthcare system of the UK Go to source
Tibolone can help ease hot flashes and improve your sex drive. It has similar side effects as HRT, including abdominal and pelvic pain, breast tenderness, and a higher risk of breast cancer. Clonidine has a milder effect on menopause symptoms, but it won’t affect your hormones. Side effects include dry mouth, drowsiness, depression, and constipation. [16] X Trustworthy Source MedlinePlus Collection of medical information sourced from the US National Library of Medicine Go to source Antidepressants may help with hot flashes,[17] X Trustworthy Source BreastCancer. org Patient-focused nonprofit organization providing resources for those affected by breast cancer Go to source but they have side effects such as dizziness, anxiety, agitation, and a reduced sex drive. Gabapentin can help treat hot flashes and insomnia during menopause. Side effects include headaches, dizziness, and sleepiness. [18] X Research source
