Count the weeks starting from the first day of your last menstrual cycle. Avoid drinking alcohol before you take your pills since it will make you dehydrated later on.

If you throw up in the first 30 minutes after taking the pill, it likely won’t work and you might have to take it again. Call your doctor to see if you need to take another dose.

Plan out the timing so that you’ll be at home resting comfortably once you take the misoprostol pills. Don’t worry if your mouth feels dry or tastes chalky once the pills are under your tongue; this is completely normal. If your kit uses the buccal form for the misoprostol, then hold them against your cheek or on the side of your mouth rather than under your tongue.

Avoid eating or drinking anything during the 30 minutes that you wait for the pills to dissolve. The buccal form of the pill only takes around 3 minutes.

If you throw up before the 30 minutes are up, they may not work. But if you throw up after the pills have dissolved and are in your system, you’re likely okay.

To take another dose, repeat the same process and set the 4 misoprostol pills under your tongue to let them dissolve for 30 minutes. If you don’t end up taking 4 extra pills but your doctor gave them to you, ask your OB/GYN what you should do with them.

Avoid taking aspirin because this can make your bleeding worse.

Bleeding will likely start 1-3 hours after you take the misoprostol pills. You’ll bleed the heaviest when your pregnancy comes out. If you see the embryo or large blood clots, don’t panic! This is normal too. Avoid using tampons because it’s harder to see how much you’re bleeding and might cause you more discomfort.

Taking a warm or hot shower can also help with any discomfort.

If your doctor gave you anti-nausea medicine, you can take this to help you feel better too. Avoid drinking alcohol after using the kit since it can dehydrate you more.

Avoid lifting heavy things so you don’t cause yourself more pain or discomfort.

If you have a fever that isn’t going away after 1 day, or you’re throwing up a lot and having trouble eating or drinking, call your OB/GYN so they can help. Don’t feel embarrassed to call your OB/GYN—they’re there to help you and can give you the best advice for how to feel better.