You are allergic to Alka-Seltzer or any of the ingredients (aspirin, citric acid, and sodium bicarbonate) You have asthma, bleeding problems, or nose irritations or polyps You are taking any other drug that includes aspirin You are pregnant, plan to become pregnant, or are breastfeeding

Your doctor might give you different dosage instructions. If that’s the case, listen to your doctor.

Use room temperature water. Cold water will slow down the fizzing, and warm water will cause excessive fizzing. [4] X Research source

You can choose from a variety of flavors like Tropical Twist and Tropical Punch.

You are taking other drugs that include aspirin or take MAOIs (typically drugs for depression or other mental health issues) You are under 12 years old You have liver disease, heart disease, high blood pressure, diabetes, thyroid problems, or glaucoma You have breathing problems, such as asthma or a persistent cough

The packages are very clearly marked, so just carefully read the label to make sure you’re purchasing what you want. You can buy Alka-Seltzer at the pharmacy, a box store, or online.

Your pain, cough, or congestion gets worse or lasts for more than 7 days Your fever gets worse or lasts for more than 3 days Redness, swelling, or a rash occurs You are dizzy, nervous, or having trouble sleeping