Do not try to treat a lump on your own.

Sometimes, abscesses can form finger-like extensions and extend into nearby tissues, making complete removal difficult. Mouth abscesses are very challenging to treat because of their location. They can swell and block the throat. Also, if the abscess breaks open, the pus could fatally choke a guinea pig. [5] X Research source Removing a cyst may be challenging as well, since the fluid inside of it may contain bacteria.

For an abscess, a complete removal is very important. If the removal is incomplete, the abscess could come back. Surgical removal of a skin tumor is often curative, meaning that no other treatment is needed to treat the tumor. [7] X Research source However, a more aggressive tumor may require additional treatment after removal.

Flushing the abscess means to fill it with a liquid solution (the antiseptic), then suction the liquid back out. Your vet may have to flush the abscess several times to make sure all of the pus is out. The antibiotic beads would be effective for 2‒6 months. [8] X Research source

Flushing the abscess periodically will help prevent the abscess from causing problems. Your vet will let you know how often the abscess should be flushed.

Guinea pigs typically need at least one round of antibiotics following surgical removal of an abscess. [13] X Research source Your vet will determine how long your guinea pig will need antibiotic treatment. To give the antibiotic pill, hold your guinea pig, open its mouth, and put the pill as far back in the mouth as you can. If you can place the pill near the molars, your guinea pig will not be able to spit it back out easily. [14] X Research source Give the full course of antibiotics. Do not stop the antibiotic treatment when your guinea pig starts looking and feeling better. This could lead to the growth of antibiotic-resistant bacteria.

Examine the incision site for signs of infection: redness, swelling, discharge. If the incision site looks abnormal, take your guinea pig to your vet for treatment.

If any of your guinea pig’s toys have sharp edges, take those out as well. Ideal toys for a guinea pig cage are empty toilet paper or paper towel rolls since they are soft and smooth. Make sure your guinea pig’s food does not have any sharp edges that could damage his gums.

Correcting dental problems in guinea pigs requires surgery. Your vet will use specialized dental instruments to trim and realign the teeth.