Wash the area gently with soap and warm water. It is important to clean the blister in case it breaks open. This will reduce the amount of dirt and bacteria on your skin nearby which could infect it. Cover the blister with a BandAid. This will reduce the pain by protecting it from contact as you use your hand.

Wash the blister with warm water and soap. Don’t scrub because you don’t want to irritate it. But run it under water and wash it gently to make sure that any dirt, bacteria, or sweat is removed. Dab iodine, hydrogen peroxide, or rubbing alcohol on the area to kill any remaining bacteria. Use a clean cotton ball and gently wipe the blister and a small area around the blister itself.

Wash a needle with soap and water. Then wipe the needle with rubbing alcohol to kill any bacteria that may be on it. You can do this by putting alcohol on a cotton swab and rubbing it on the needle. The alcohol will quickly evaporate in the air. Slowly and carefully use the needle to make a tiny hole in the edge of the blister. Make the hole in the layer of skin that is on top of the fluid. The fluid will flow out of the hole. Do not remove the layer of skin that was on top of the bubble. Leave it so that it covers and protects the irritated skin beneath it.

Washing the fluid from the blister off your hand. Run your hand under warm water and wash gently with soap. Gently smearing Vaseline or an antibiotic ointment on the drained blister. They are available at your local pharmacy. You can purchase it without a prescription. Applying a clean BandAid over the blister. Be careful that the adhesive areas of the BandAid do not stick to the flap of skin that was on top of the blister. You don’t want to rip the skin off when you remove the BandAid. Look for for the kind of BandAids that have a square of gauze with adhesive on all four sides, rather than the kind that are strips with adhesive on only two sides. This will better protect your wound, as all four sides of the bandage will be sealed.

Increasing redness, swelling, warmth or pain over time Pus seeping from the wound. This does not include fluid that came out of the blister when you popped it.

Wrap an ice pack in a thin towel and apply it to the blister for about 20 minutes. If you do not have an ice pack handy, you can wrap a bag of frozen peas or corn in a towel and use that.

A burn, including a sunburn An allergic reaction to medication Atopic dermatitis, also called eczema An infection such as chickenpox, shingles, herpes, impetigo

Raking leaves Shoveling snow Gardening Moving furniture or other heavy lifting

Use moleskin or another form of soft padding. You can purchase it at your local drugstore. Fold the moleskin or padding in half. Cut a half circle out along the fold. The cut should be the diameter of the area you want to protect. Unfold the moleskin. You will have a small round hole in the center that is the size of the area that is forming a blister. Fix the moleskin to your hand with the sensitive area exposed through the hole. The padding around it will take the pressure off and prevent a blister from forming.

Rowing[10] X Research source Gymnastics Weight lifting Horseback riding Climbing